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DC Field | Value | Language |
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dc.contributor.author | Sinha, Supurna | - |
dc.contributor.author | Samuel, J. | - |
dc.date.accessioned | 2012-05-28T10:41:32Z | - |
dc.date.available | 2012-05-28T10:41:32Z | - |
dc.date.issued | 2012-04 | - |
dc.identifier.citation | Physical Review E, 2012, Vol.85, p041802 | en |
dc.identifier.issn | 1539-3755 | - |
dc.identifier.issn | 1550-2376 (Online) | - |
dc.identifier.uri | http://hdl.handle.net/2289/4546 | - |
dc.description | Open Access | en |
dc.description.abstract | We present an analytical study of the role of thermal fluctuations in shaping molecular elastic properties of semiflexible polymers. Our study interpolates between mechanics and statistical mechanics in a controlled way and shows how thermal fluctuations modify the elastic properties of biopolymers. We present a study of the minimum-energy configurations with explicit expressions for their energy and writhe and plots of the extension versus link for these configurations and a study of fluctuations around the local minima of energy and approximate analytical formulas for the free energy of stretched twisted polymers. The central result of our study is a closed-form expression for the leading thermal fluctuation correction to the free energy around the nonperturbative writhing family solution for the configuration of a biopolymer. From the derived formulas, the predictions of the wormlike chain model for molecular elasticity can be worked out for a comparison against numerical simulations and experiments. | en |
dc.language.iso | en | en |
dc.publisher | American Physical Society | en |
dc.relation.uri | http://dx.doi.org/10.1103/PhysRevE.85.041802 | en |
dc.relation.uri | http://adsabs.harvard.edu/abs/2012PhRvE..85d1802S | en |
dc.rights | 2012 The American Physical Society | en |
dc.title | Biopolymer elasticity: Mechanics and thermal fluctuations | en |
dc.type | Article | en |
Appears in Collections: | Research Papers (TP) |
Files in This Item:
File | Description | Size | Format | |
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2012_PRE_V85_p041802.pdf | Open Access. | 410.89 kB | Adobe PDF | View/Open |
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