Dynamics of membrane tethers reveal novel aspects of cytoskeleton-membrane interactions in axons.

Datar, Anagha S.; Bornschogol, Thomas; Bassereau, Patricia; Prost, Jacques; Pullarkat, Pramod A.

Please use this identifier to cite or link to this item: http://hdl.handle.net/2289/6249

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DC Field	Value	Language
dc.contributor.author	Datar, Anagha S.	-
dc.contributor.author	Bornschogol, Thomas	-
dc.contributor.author	Bassereau, Patricia	-
dc.contributor.author	Prost, Jacques	-
dc.contributor.author	Pullarkat, Pramod A.	-
dc.date.accessioned	2015-06-11T12:34:11Z	-
dc.date.available	2015-06-11T12:34:11Z	-
dc.date.issued	2015-02	-
dc.identifier.citation	Biophysical Journal, 2015, Vol.108, p 489-497	en
dc.identifier.issn	0006-3495	-
dc.identifier.uri	http://hdl.handle.net/2289/6249	-
dc.description	Restricted Access.	en
dc.description.abstract	Mechanical properties of cell membranes are known to be significantly influenced by the underlying cortical cytoskeleton. The technique of pulling membrane tethers from cells is one of the most effective ways of studying the membrane mechanics and the membrane-cortex interaction. In this article, we show that axon membranes make an interesting system to explore as they exhibit both free membrane-like behavior where the tether-membrane junction is movable on the surface of the axons (unlike many other cell membranes) as well as cell-like behavior where there are transient and spontaneous eruptions in the tether force that vanish when F-actin is depolymerized. We analyze the passive and spontaneous responses of axonal membrane tethers and propose theoretical models to explain the observed behavior	en
dc.language.iso	en	en
dc.publisher	Biophysical Society	en
dc.relation.uri	http://dx.doi.org/10.1016/j.bpj.2014.11.3480	en
dc.rights	Restricted Access.	en
dc.subject	12months	en
dc.title	Dynamics of membrane tethers reveal novel aspects of cytoskeleton-membrane interactions in axons.	en
dc.type	Article	en
Appears in Collections:	Research Papers (SCM)

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