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http://hdl.handle.net/2289/5501Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Bernal, Roberto | - |
| dc.contributor.author | Pullarkat, Pramod A. | - |
| dc.contributor.author | Melo, Francisco | - |
| dc.date.accessioned | 2013-03-26T05:34:45Z | - |
| dc.date.available | 2013-03-26T05:34:45Z | - |
| dc.date.issued | 2007 | - |
| dc.identifier.citation | Physical Review Letters, 2007, Vol.99, p018301-1 | en |
| dc.identifier.issn | 0031-9007 | - |
| dc.identifier.issn | 1079-7114(Online) | - |
| dc.identifier.uri | http://hdl.handle.net/2289/5501 | - |
| dc.description | Restricted Access. | en |
| dc.description.abstract | The mechanical response of PC12 neurites under tension is investigated using a microneedle technique. Elastic response, viscoelastic relaxation, and active contraction are observed. The mechanical model proposed by Dennerll et al. [ J. Cell Biol. 109 3073 (1989)], which involves three mechanical devices—a stiff spring κ coupled with a Voigt element that includes a less stiff spring k and a dashpot γ—has been improved by adding a new element to describe the main features of the contraction of axons. This element, which represents the action of molecular motors, acts in parallel with viscous forces defining a global tension response of axons T against elongation rates δ˙k. Under certain conditions, axons show a transition from a viscoelastic elongation to active contraction, suggesting the presence of a negative elongation rate sensitivity in the curve T vs δ˙k. | en |
| dc.language.iso | en | en |
| dc.publisher | American Physical Society | en |
| dc.relation.uri | http://dx.doi.org/10.1103/PhysRevLett.99.018301 | en |
| dc.rights | 2007 American Physical Society | en |
| dc.title | Mechanical Properties of Axons | en |
| dc.type | Article | en |
| Appears in Collections: | Research Papers (SCM) | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2007_PhysRevLett_Vol.99_p018301.pdf Restricted Access | Restricted Access | 450.72 kB | Adobe PDF | View/Open Request a copy |
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