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http://hdl.handle.net/2289/4625| Title: | Osmotically driven shape transformations in axons |
| Authors: | Pullarkat, Pramod A. Dommersnes, Paul Fernandez, Pablo Joanny, J.F. Ott, Albrecht |
| Issue Date: | 2006 |
| Publisher: | American Physical Society |
| Citation: | Physical Review Letters, 2006, Vol.96, p048104-1 |
| Abstract: | We report a cylindrical-peristaltic shape transformation in axons exposed to a controlled osmotic perturbation. The peristaltic shape relaxes and the axon recovers its original geometry within minutes. We show that the shape instability depends critically on the swelling rate and that volume and membrane area regulation are responsible for the shape relaxation. We propose that volume regulation occurs via leakage of ions driven by elastic pressure, and analyze the peristaltic shape dynamics taking into account the internal structure of the axon. The results obtained provide a framework for understanding peristaltic shape dynamics in nerve fibers occurring in vivo. |
| Description: | Restricted Access. |
| URI: | http://hdl.handle.net/2289/4625 |
| ISSN: | 0031-9007 1079-7114 (Onnline) |
| Alternative Location: | http://arxiv.org/abs/physics/0603122 http://dx.doi.org/10.1103/PhysRevLett.96.048104 |
| Copyright: | 2006, American Physical Society |
| Appears in Collections: | Research Papers (SCM) |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| 2006_PhysRevLett_V96_p048104.pdf Restricted Access | Restricted Access | 367.6 kB | Adobe PDF | View/Open Request a copy |
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