Please use this identifier to cite or link to this item: http://hdl.handle.net/2289/4206
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dc.contributor.authorMuhuri, Sudipto-
dc.contributor.authorShagolsem, Lenin-
dc.contributor.authorRao, Madan-
dc.date.accessioned2011-12-15T05:27:22Z-
dc.date.available2011-12-15T05:27:22Z-
dc.date.issued2011-09-
dc.identifier.citationPhysical Review E, 2011, Vol.84, 031921en
dc.identifier.issn1539-3755-
dc.identifier.issn1550-2376 (Online)-
dc.identifier.urihttp://hdl.handle.net/2289/4206-
dc.descriptionOpen Accessen
dc.description.abstractWe study a minimal lattice model which describes bidirectional transport of “particles” driven along a onedimensional track, as is observed in microtubule based, motor protein driven bidirectional transport of cargo vesicles, lipid bodies, and organelles such asmitochondria. Thisminimal model, a multispecies totally asymmetric exclusion process (TASEP) with directional switching, can provide a framework for understanding the interplay between the switching dynamics of individual particles and the collectivemovement of particles in one dimension. When switching is much faster than translocation, the steady-state density and current profiles of the particles are homogeneous in the bulk and are well described by mean-field (MF) theory, as determined by comparison to a Monte Carlo simulation. In this limit, we can map this model to the exactly solvable partially asymmetric exclusion-process (PASEP) model. Away from this fast switching regime the MF theory fails, although the average bulk density profile still remains homogeneous. We study the steady-state behavior as a function of the ratio of the translocation and net switching rates Q and find a unique first-order phase transition at a finite Q associated with a discontinuous change of the bulk density.When the switching rate is decreased further (keeping translocation rate fixed), the system approaches a jammed phase with a net current that tends to zero as J ∼ 1/Q. We numerically construct the phase diagram for finite Q.en
dc.language.isoenen
dc.publisherThe Americal Physical Societyen
dc.relation.urihttp://adsabs.harvard.edu/abs/2011PhRvE..84c1921Men
dc.relation.urihttp://dx.doi.org/10.1103/PhysRevE.84.031921en
dc.rights2011 The American Physical Societyen
dc.titleBidirectional transport in a multispecies totally asymmetric exclusion-process modelen
dc.typeArticleen
Appears in Collections:Research Papers (SCM)

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