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Please use this identifier to cite or link to this item: http://hdl.handle.net/2289/4131

Title: Spontaneously forming unilamellar nano-sized vesicles-polydispersity, size, shape and stability
Authors: Nieh, M.P.
Raghunathan, V.A.
Huang, C.Y.
Pencer, J.
Harroun, T.A.
Katsaras, J.
Keywords: unilameller vesicles
Phospolipids
small angle neutron scattering
polydispersity
anti-cancer drug delivery
nano particles
DMPC
DHPC
Issue Date: Jun-2007
Publisher: CRC Press
Citation: NSTI - Nanotech NSTI Nanotech: Technical Proceedings, 2007, Vol.2, p709
Abstract: Unilameller vesicles(ULV) made up of biologically relevant materials can serve as carries for drug delivery or gene therapy. Compared to extrusion and sonication, methods traditionally used for producing ULV, spontaneous formation offers a cost effective alternative for ULV mass production.Moreover, the fact that these ULV are most likely, thermodynamically stable assures that the final product will have an extended shelf life. Here we report recent work on ULV formed from long and short chain phospolipids and address some of the important factors that affect their polydispersity, size, shape and Stability.
Description: Restricted Access.
URI: http://hdl.handle.net/2289/4131
ISBN: 0976798573
Copyright: 2007 CRC Press
Appears in Collections:Research Papers (SCM)

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