Please use this identifier to cite or link to this item:
|Title:||Buckling, stiffening, and negative dissipation in the dynamics of a biopolymer in an active medium|
Kas, Josef A.
neuronal growth cone
|Publisher:||National Academy of Sciences|
|Citation:||Proceedings of the National Academy of Sciences, 2009, Vol.106, p19776|
|Abstract:||We present a generic theory for the dynamics of a stiff filament under tension, in an active medium with orientational correlations, such as a microtubule in contractile actin. In sharp contrast to the case of a passive medium, we find the filament can stiffen, and possibly oscillate or buckle, depending on both the contractile or tensile nature of the activity and the filament-medium anchoring interaction. We also demonstrate a strong violation of the fluctuation–dissipation (FD) relation in the effective dynamics of the filament, including a negative FD ratio. Our approach is also of relevance to the dynamics of axons, and our model equations bear a remarkable formal similarity to those in recent work [Martin P, Hudspeth AJ, Juelicher F (2001) Proc Natl Acad Sci USA 98:14380–14385] on auditory hair cells. Detailed tests of our predictions can be made by using a single filament in actomyosin extracts or bacterial suspensions.|
|Copyright:||2009 National Academy of Sciences|
|Appears in Collections:||Research Papers (TP)|
Files in This Item:
|2009_Proceedings of the national academy of scicne -V_106_19776-9.pdf|
|Restricted Access||422.57 kB||Adobe PDF||View/Open Request a copy|
Items in RRI Digital Repository are protected by copyright, with all rights reserved, unless otherwise indicated.