Magnetically alignable phase of phospholipid "Bicelle" mixtures Is a chiral nematic made up of wormlike micelles

Nieh, M.P.; Raghunathan, V.A.; Glinka, C.J.; Harroun, T.A.; Pabst, G.; Katsaras, J.

Please use this identifier to cite or link to this item: http://hdl.handle.net/2289/2860

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DC Field	Value	Language
dc.contributor.author	Nieh, M.P.	-
dc.contributor.author	Raghunathan, V.A.	-
dc.contributor.author	Glinka, C.J.	-
dc.contributor.author	Harroun, T.A.	-
dc.contributor.author	Pabst, G.	-
dc.contributor.author	Katsaras, J.	-
dc.date.accessioned	2007-06-15T04:41:27Z	-
dc.date.available	2007-06-15T04:41:27Z	-
dc.date.issued	2004	-
dc.identifier.citation	Langmuir, 2004, Vol.20, p7893-7897.	en
dc.identifier.issn	0743-7463	-
dc.identifier.issn	1520-5827 (Online)	-
dc.identifier.uri	http://hdl.handle.net/2289/2860	-
dc.description	Restricted Access.	en
dc.description.abstract	We have studied the phase behavior of binary mixtures of long- and short-chain lipids, namely, dimyristoyl phosphatidylcholine (DMPC) and dihexanoyl phosphatidylcholine (DHPC), using optical microscopy and small-angle neutron scattering. Samples with a total lipid content of 25 wt %, corresponding to ratios Q ([DMPC]/[DHPC]) of 5, 3.2, and 2, are found to exhibit an isotropic (I) chiral nematic (N) lamellar phase sequence on increasing temperature. The I-N transition coincides with the chain melting transition of DMPC at Q = 5 and 3.2, but the N* phase forms at a higher temperature for Q = 2. All three samples form multilamellar vesicles in the lamellar phase. Our results show that disklike "bicellar" aggregates occur only in the lower temperature isotropic phase and not in the higher temperature magnetically alignable N* phase, where they were previously believed to exist. The N* phase is found to consist of long, flexible wormlike micelles, their entanglement resulting in the very high viscosity of this phase.	en
dc.format.extent	323243 bytes	-
dc.format.mimetype	application/pdf	-
dc.language.iso	en	en
dc.publisher	American Chemical Society	en
dc.relation.uri	http://dx.doi.org/10.1021/la048641l	en
dc.rights	2004 American Chemical Society	en
dc.title	Magnetically alignable phase of phospholipid "Bicelle" mixtures Is a chiral nematic made up of wormlike micelles	en
dc.type	Article	en
Appears in Collections:	Research Papers (SCM)

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