Electrochemical oxidation of L-dopa at a carbon paste electrode

Mascarenhas, Ronald J.; Reddy, K.V.; Kumaraswamy, B.E.; Sherigara, B.S.; Lakshminarayanan, V.

Please use this identifier to cite or link to this item: http://hdl.handle.net/2289/2281

Full metadata record

DC Field	Value	Language
dc.contributor.author	Mascarenhas, Ronald J.	-
dc.contributor.author	Reddy, K.V.	-
dc.contributor.author	Kumaraswamy, B.E.	-
dc.contributor.author	Sherigara, B.S.	-
dc.contributor.author	Lakshminarayanan, V.	-
dc.date.accessioned	2007-04-24T10:54:19Z	-
dc.date.available	2007-04-24T10:54:19Z	-
dc.date.issued	2005-08-08	-
dc.identifier.citation	Bulletin of Electrochemistry, 2005, Vol.21, p341-345	en
dc.identifier.issn	0256-1654	-
dc.identifier.uri	http://hdl.handle.net/2289/2281	-
dc.description	Restricted Access.	en
dc.description.abstract	The electrochemical oxidation pathway of levodopa and methyl dopa at a carbon paste electrode in a pyrophosphate buffer medium has been studied. The catechol moiety in both the compounds undergoes a two-electron oxidation to give dopaquirtone. The effects of varying pH, sweep rate. concentration of the electroactive species and temperature on the electrochemical behavior of levodopa and methyl dopa have been discussed. Much sharper peaks were obtained on carbon paste electrode as compared with glassy carbon electrode. The signal was enhanced on addition of cationic and anionic surfactants while non-ionic surfactant decreased the peak current This behavior, which is different from that observed at the glassy carbon electrode, makes it possible to determine wry low concentrations of levodopa. The effect of addition of surfactants can be a consideration for the selective determination of levodopa in the presence of ascorbic acid present in biological systems. A method for the electrochemical determination of dopa in pharmaceutical formulations is developed using differential pulse voltammetry.	en
dc.format.extent	338629 bytes	-
dc.format.mimetype	application/pdf	-
dc.language.iso	en	en
dc.publisher	Central Electrochemical Research Institute	en
dc.rights	2005 Central Electrochemical Research Institute	en
dc.subject	Dopa	en
dc.subject	Electrochemical oxidation	en
dc.subject	Carbon paste electrode	en
dc.subject	Surfactant	en
dc.subject	Differential pulse voltammetry	en
dc.title	Electrochemical oxidation of L-dopa at a carbon paste electrode	en
dc.type	Article	en
Appears in Collections:	Research Papers (SCM)

Files in This Item:

File	Description	Size	Format
2005 Bull. of Elctrochemistry V21 p341-345.pdf Restricted Access	Restricted Access	330.69 kB	Adobe PDF	View/Open Request a copy

Show simple item record