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Title: Cholesterol-induced modulated phase in phospholipid membranes
Authors: Karmakar, Sanat
Raghunathan, V.A.
Issue Date: 2003
Publisher: The American Physical Society
Citation: Physical Review Letters, 2003, Vol.91, 098102
Abstract: We report the observation of a cholesterol-induced modulated phase (Pbeta) in dipalmitoyl phosphatidylcholine bilayers. It occurs below the main transition of the lipid at cholesterol concentrations of around 15 to 20 mol % and is distinct from the ripple (Pbeta[prime]) phase found in between the main and pretransitions at lower cholesterol concentrations. An electron density map of this phase, constructed from x-ray diffraction data from oriented multilayers, shows that the bilayers in this phase have a one-dimensional periodic height modulation with an amplitude of about 2.5 Å. A partial phase diagram of the system deduced from diffraction data is in broad agreement with earlier studies.
ISSN: ISSN 1079-7114 (online)
0031-9007 (print)
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Copyright: (2003) by the American Physical Society
Appears in Collections:Research Papers (SCM)

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