Relationship between the unbinding and main transition temperatures of  phospholipid bilayers under pressure.

Harroun, T.A.; Nieh, M.P.; Watson, M.J.; Raghunathan, V.A.; Pabst, G.; Morrow, M.

Please use this identifier to cite or link to this item: http://hdl.handle.net/2289/1277

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DC Field	Value	Language
dc.contributor.author	Harroun, T.A.	-
dc.contributor.author	Nieh, M.P.	-
dc.contributor.author	Watson, M.J.	-
dc.contributor.author	Raghunathan, V.A.	-
dc.contributor.author	Pabst, G.	-
dc.contributor.author	Morrow, M.	-
dc.date.accessioned	2006-05-18T05:29:32Z	-
dc.date.available	2006-05-18T05:29:32Z	-
dc.date.issued	2004-03-19	-
dc.identifier.citation	Physical Review E, 2004, Vol.69, 031906-	en
dc.identifier.issn	ISSN 1550-2376 (online)	-
dc.identifier.issn	1539-3755	-
dc.identifier.uri	http://hdl.handle.net/2289/1277	-
dc.description.abstract	Using neutron diffraction and a specially constructed high pressure cell suitable for aligned multibilayer systems, we have studied, as a function of pressure, the much observed anomalous swelling regime in dimyristoyl- and dilauroyl-phosphatidylcholine bilayers, DMPC and DLPC, respectively. We have also reanalyzed data from a number of previously published experiments and have arrived at the following conclusions. (a) The power law behavior describing anomalous swelling is preserved in all PC bilayers up to a hydrostatic pressure of 240 MPa. (b) As a function of increasing pressure there is a concomitant decrease in the anomalous swelling of DMPC bilayers. (c) For PC lipids with hydrocarbon chains >=13 carbons the theoretical unbinding transition temperature T[small star, filled] is coupled to the main gel-to-liquid crystalline transition temperature TM. (d) DLPC is intrinsically different from the other lipids studied in that its T[small star, filled] is not coupled to TM. (e) For DLPC bilayers we predict a hydrostatic pressure (>290 MPa) where unbinding may occur.	en
dc.format.extent	105462 bytes	-
dc.format.mimetype	application/pdf	-
dc.language.iso	en	en
dc.publisher	The American Physical Society	en
dc.relation.uri	http://link.aps.org/abstract/PRE/v69/e031906	en
dc.rights	(2004) by the American Physical Society	en
dc.title	Relationship between the unbinding and main transition temperatures of phospholipid bilayers under pressure.	en
dc.type	Article	en
Appears in Collections:	Research Papers (SCM)

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