Title:	Nanomechanics of membrane tubulation and DNA assembly
Authors:	Roopa, T. Shivashankar, G.V.
Issue Date:	10-Mar-2003
Publisher:	The American Institute of Physics
Citation:	Applied Physics Letters, 2003, Vol.82, p1631-1633
Abstract:	We report an interesting regime of tubule formation in multilamellar membrane vesicles. An optically trapped bead is used to apply a localized subpicoNewton force on a cationic vesicle to form a membrane tubule. The force extension curves reveal a saturation phase, with the tubule length extending up to tens of microns, beyond a threshold force 0.6±0.2 pN. We then use the tubule as a sensor for monitoring the dynamics of charge induced DNA integration on cationic membrane vesicles. Our results may also have applications in the development of nanowires and nanofluidic devices.
URI:	http://hdl.handle.net/2289/1269
ISSN:	0003-6951
Alternative Location:	http://link.aip.org/link/?apl/82/1631
Copyright:	(2003) by the American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.
Appears in Collections:	Research Papers (SCM)

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