Transport, Clustering and Chemical Kinetics of cell surface molecules influenced by actomyosin cortex
| dc.contributor.advisor | Rao, Madan | |
| dc.contributor.advisor | Pullarkat, Pramod A | |
| dc.contributor.author | Hossein, Raj S K | |
| dc.date.accessioned | 2022-04-01T11:09:14Z | |
| dc.date.available | 2022-04-01T11:09:14Z | |
| dc.date.issued | 2022-03 | |
| dc.description | Open Access | en_US |
| dc.description.sponsorship | The cell membrane is the gateway between the outside and the inside of the cell. The cell membrane, a multicomponent bilayer, comprising lipids, proteins and sugars, plays an essential role in signalling or transfer of information, sorting or the processing of information, and endo/exo-cytosis or the transfer of molecules, together with the transfer of small molecules and ions. These fundamental cellular processes are crucially dependent on the spatio-temporal organization and control of membrane molecules. Given the importance of molecular organization in the membrane, not surprisingly, there have been many studies devoted to this, and many models proposed to describe the organization and regulation of the cell membrane. Amongst these, the most in uential models have been the Fluid Mosaic and the Lipid Raft models - both these models are grounded in the equilibrium physics of the lipid membrane and treat the cell membrane, with its constituent lipids and proteins as an independent organ. However, many recent experiments have established that the plasma membrane is intimately coupled to the actomyosin cortex. This actomyosin cortex is a thin, 200 nm, uid layer adjoining the plasma membrane, that largely comprises of actin cytoskeleton and myosin motors. Many cell membrane molecules can bind, directly or indirectly, to cortical actin. | en_US |
| dc.identifier.citation | Ph.D. Thesis, Jawaharlal Nehru University, New Delhi, 2022 | en_US |
| dc.identifier.uri | http://hdl.handle.net/2289/7916 | |
| dc.language.iso | en | en_US |
| dc.publisher | Raman Research Institute, Bangalore. | en_US |
| dc.rights | This thesis is posted here with the permission of the author. Personal use of this material is permitted. Any other use requires prior permission of the author. By choosing to view this document, you agree to all provisions of the copyright laws protecting it. | en_US |
| dc.subject.classification | Theoretical Physics | |
| dc.title | Transport, Clustering and Chemical Kinetics of cell surface molecules influenced by actomyosin cortex | en_US |
| dc.type | Thesis | en_US |