Cholesterol-induced modulated phase in phospholipid membranes

dc.contributor.author	Karmakar, Sanat
dc.contributor.author	Raghunathan, V.A.
dc.date.accessioned	2006-05-18T11:27:07Z
dc.date.available	2006-05-18T11:27:07Z
dc.date.issued	2003
dc.description.abstract	We report the observation of a cholesterol-induced modulated phase (Pbeta) in dipalmitoyl phosphatidylcholine bilayers. It occurs below the main transition of the lipid at cholesterol concentrations of around 15 to 20 mol % and is distinct from the ripple (Pbeta[prime]) phase found in between the main and pretransitions at lower cholesterol concentrations. An electron density map of this phase, constructed from x-ray diffraction data from oriented multilayers, shows that the bilayers in this phase have a one-dimensional periodic height modulation with an amplitude of about 2.5 Å. A partial phase diagram of the system deduced from diffraction data is in broad agreement with earlier studies.	en
dc.format.extent	509617 bytes
dc.format.mimetype	application/pdf
dc.identifier.citation	Physical Review Letters, 2003, Vol.91, 098102	en
dc.identifier.issn	ISSN 1079-7114 (online)
dc.identifier.issn	0031-9007 (print)
dc.identifier.uri	http://hdl.handle.net/2289/1283
dc.language.iso	en	en
dc.publisher	The American Physical Society	en
dc.relation.uri	http://link.aps.org/abstract/PRL/v91/e098102	en
dc.rights	(2003) by the American Physical Society	en
dc.title	Cholesterol-induced modulated phase in phospholipid membranes	en
dc.type	Article	en

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