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Spontaneously forming unilamellar nano-sized vesicles-polydispersity, size, shape and stability

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dc.contributor.authorNieh, M.P.
dc.contributor.authorRaghunathan, V.A.
dc.contributor.authorHuang, C.Y.
dc.contributor.authorPencer, J.
dc.contributor.authorHarroun, T.A.
dc.contributor.authorKatsaras, J.
dc.date.accessioned2011-08-23T10:14:15Z
dc.date.available2011-08-23T10:14:15Z
dc.date.issued2007-06
dc.descriptionRestricted Access.en
dc.description.abstractUnilameller vesicles(ULV) made up of biologically relevant materials can serve as carries for drug delivery or gene therapy. Compared to extrusion and sonication, methods traditionally used for producing ULV, spontaneous formation offers a cost effective alternative for ULV mass production.Moreover, the fact that these ULV are most likely, thermodynamically stable assures that the final product will have an extended shelf life. Here we report recent work on ULV formed from long and short chain phospolipids and address some of the important factors that affect their polydispersity, size, shape and Stability.en
dc.identifier.citationNSTI - Nanotech NSTI Nanotech: Technical Proceedings, 2007, Vol.2, p709en
dc.identifier.isbn0976798573
dc.identifier.urihttp://hdl.handle.net/2289/4131
dc.language.isoenen
dc.publisherCRC Pressen
dc.rights2007 CRC Pressen
dc.subjectunilameller vesiclesen
dc.subjectPhospolipidsen
dc.subjectsmall angle neutron scatteringen
dc.subjectpolydispersityen
dc.subjectanti-cancer drug deliveryen
dc.subjectnano particlesen
dc.subjectDMPCen
dc.subjectDHPCen
dc.titleSpontaneously forming unilamellar nano-sized vesicles-polydispersity, size, shape and stabilityen
dc.typeBook chapteren

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