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Nanomechanics of membrane tubulation and DNA assembly

dc.contributor.authorRoopa, T.
dc.contributor.authorShivashankar, G.V.
dc.date.accessioned2006-05-16T11:19:36Z
dc.date.available2006-05-16T11:19:36Z
dc.date.issued2003-03-10
dc.description.abstractWe report an interesting regime of tubule formation in multilamellar membrane vesicles. An optically trapped bead is used to apply a localized subpicoNewton force on a cationic vesicle to form a membrane tubule. The force extension curves reveal a saturation phase, with the tubule length extending up to tens of microns, beyond a threshold force 0.6±0.2 pN. We then use the tubule as a sensor for monitoring the dynamics of charge induced DNA integration on cationic membrane vesicles. Our results may also have applications in the development of nanowires and nanofluidic devices.en
dc.format.extent304603 bytes
dc.format.mimetypeapplication/pdf
dc.identifier.citationApplied Physics Letters, 2003, Vol.82, p1631-1633en
dc.identifier.issn0003-6951
dc.identifier.urihttp://hdl.handle.net/2289/1269
dc.language.isoenen
dc.publisherThe American Institute of Physicsen
dc.relation.urihttp://link.aip.org/link/?apl/82/1631en
dc.rights(2003) by the American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics.en
dc.titleNanomechanics of membrane tubulation and DNA assemblyen
dc.typeArticleen

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