RRI Digital Repository >
06. Soft Condensed Matter >
Research Papers (SCM) >
Please use this identifier to cite or link to this item:
|Title: ||Spontaneously formed unilamellar vesicles with path-dependent size distribution|
|Authors: ||Nieh, M.P.|
Kline, Steve R.
|Issue Date: ||17-Jun-2005 |
|Publisher: ||American Chemical Society|
|Citation: ||Langmuir, 2005, Vol. 21, p6656-6661|
|Abstract: ||We observe the spontaneous formation of path-dependent monodisperse and polydisperse phospholipid unilamellar vesicles (ULV) from two different equilibrium morphologies specifically, disklike micelles and extended lamellae, respectively. On heating beyond a temperature Tc, low temperature disklike micelles, or so-called bicelles, transform into lamellae. Dilution of the lamellar phase, at a fixed temperature, results in a complete unbinding transition and the formation of polydisperse ULV, demonstrating the instability of the lamellar phase. On the other hand, heating of a dilute bicellar phase above Tc results in monodisperse ULV, which on cooling revert back to bicelles for lipid concentrations 0.5 wt % and transform into oblate ellipsoids for = 0.1 wt %, a morphology not previously seen in "bicellar" lipid mixtures. Monodisperse ULV reform on heating of the oblate ellipsoids.|
|Description: ||Restricted Access.|
|Alternative Location: ||http://dx.doi.org/10.1021/la0508994|
|Copyright: ||2005 American Chemical Society|
|Appears in Collections:||Research Papers (SCM)|
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.