Title:	Synthesis and mesomorphic characterization of novel liquid crystals derived from bioactive natural sterols
Authors:	Bhat, Vanishree, S. Swamynathan, K. Kumar, Sandeep
Keywords:	Liquid crystals Stigmasterol Ergosterol Cholesterol Mercaptoalkyl benzoates
Issue Date:	Mar-2021
Publisher:	Elesvier B.V.
Citation:	Journal of Molecular Liquids, 2021, Vol.326, p115216
Abstract:	Steroids are one of the prominent categories of secondary metabolites that are renowned for their biological activities. The steroidal derivatives are well known for their inherent potential to exhibit diverse esophases. In this report, we have shown the mesomorphic behavior of some novel 4-mercaptoalkyl benzoates of olesterol, stigmasterol and ergosterol. This study mainly focuses on the effect of the steroidal skeleton, as well as the effect of replacement of oxygen with the sulfur atom in the side chains on their mesogenic behavior. The cholesteryl analogs were found to show smectic, cholesteric and blue phases; whereas the stigmasterol and ergosterol derivatives were found to be smectogenic in nature. The tigmasterol derivatives were found to exhibit significantly lower clearing temperatures compared to orresponding cholesterol and ergosterol analogs. Also, the replacement of the oxygen atom with sulfur in the cholesteryl derivatives resulted in a considerable reduction in their clearing temperatures.
Description:	Restricted Access.
URI:	http://hdl.handle.net/2289/7726
ISSN:	0167-7322
Alternative Location:	https://doi.org/10.1016/j.molliq.2020.115216
Copyright:	2021 Elsevier B.V.
Appears in Collections:	Research Papers (SCM)

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