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Title: Biological cell monolayer shearing apparatus for diagnostic purposes
Authors: Pullarkat, Pramod
Ott, Albrecht
Aksel, Nuri
Traenkle, Benjamin
Fernandez, N.
Heymann, B
Issue Date: 19-Feb-2009
Citation: WO 2009/021923 Al, 2009
Abstract: The present invention is directed to a method for determining the mechanical properties of biological cells wherein a cell sample containing microbeads having a diameter about the average diameter of the cell's nucleus is introduced into a gap formed by two essentially parallel and horizontal plates, a cell and microbead monolayer is formed, shear stress is applied to said monolayer and the mechanical responses of said monolayer is measured. The present invention is further directed to a device for performing the method.
Description: Open Access
Appears in Collections:Patents (SCM)

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